Scientific References
Nutribeauti Superfood
- The antioxidant, immunomodulatory and anti-inflammatory activities of Spirulina: an overview. Wu Q et al. Arch toxicol 2016 Aug 90(8):1817-40
- Spirulina: 11 health benefits and nutrition. Medical News Today Dec 2018
- Effects of Spirulina consumption on body weight, blood plessure and endothelial function in overweight hypertensive Caucasians: a double blind, placebo controlled, randomized trial. Miczke A et al Eur Rev Med Pharmacol Sci 2016; 20(1):150-156
- Spirulina protects against hepatic inflammation in aging: an effect related to the modulation of the gut microbiota? Audrey M Neyrinck et al. Nutrients 2017 Jun; 9(6):633
- Quantifying the effects of Spirulina supplementation on plasma lipid and glucose concentrations, body weight and blood pressure. Huang H et al. Diabetes Metab Syndr Obes, 2018; 11:729-742
- A systemic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations. Serban MC et al. Clin Nutr 2016, Aug; 35(4):842-51
- Health benefits of blue-green algae: prevention of cardiovascular disease and nonalcoholic fatty liver disease. Chai Siah Ku et al. J Med Food, 2013 Feb; 16 (2):103-111
- The hepatoprotective and hypolipidemic effects od Spirulina (Arthrospira platensis) supplementation in a Cretan population with nonalcoholic fatty liver disease: a prospective pilot study. Mazokopakis EE et al. Ann Gastroenterol 2014; 27 (4): 387-394
- The effects of Spirulina on allergic rhiritis. Cingic eta al. Eu Arch Otorhinolaryngol, 2008 Oct; 265 (10): 1219-23
- Spirulina as a main source of tryptophan for mental illness: Improving level of serotonin through tryptophan supplementation. Sasie,Sileshi (2018). Global Journal of Medicine and Public Health GJMEDPH 2018; Vol 7, (2).
- Preclinical antitoxic properties of Spirulina (Arthrospira). E Martínez-Galero. Pharmaceutical Biology, 2016; 54:8, 1345-53
- Use of silicon for skin and hair care: an approach of chemical forms available and efficacy. Advincula de Araújo et al. An. Bras. Dermatol. vol.91 no.3 Rio de Janeiro May/June 2016
- Update on the possible nutritional importance of silicon. FH Nielsen - Journal of Trace Elements in Medicine and Biology, 2014 – Elsevier Volume 28, Issue 4, October 2014, Pages 379-382
- The silicon content of beer and its bioavailability in healthy volunteers. Sripanyakorn S, Jugdaohsingh R, Elliott H, Walker C, Mehta P, Shoukru S, et al. Br J Nutr. 2004;91 :403-9.
ageLOC® Meta
1. Araújo J, Cai J, Stevens J. Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition
Examination Survey 2009–2016. Metab Syndr Relat Disord. 2019;17(1):46–52. doi:10.1089/met.2018.0105
2. Sebastian RS, Wilkinson Enns C, Goldman JD, et al. A New Database Facilitates Characterization of Flavonoid Intake, Sources, and Positive Associations with Diet Quality among
US Adults. J Nutr. 2015;145(6):1239–1248. doi:10.3945/ jn.115.213025
3. Azzini E, Giacometti J, Russo GL. Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies. Oxid Med Cell Longev. 2017;2017:2740364. doi:10.1155/2017/2740364
4. Cremonini E, Mastaloudis A, Hester SN, et al. Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. Food Funct. 2017;8(8):2915–2923. doi:10.1039/c7fo00625j
5. Cremonini E, Daveri E, Mastaloudis A, et al. Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis. Redox Biol. 2019;26:101269. doi:10.1016/j.redox.2019.101269
6. Daveri E, Cremonini E, Mastaloudis A, et al. Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice. Redox Biol. 2018;18:16–24. doi:10.1016/j.redox.2018.05.012
7. Hester SN, Mastaloudis A, Gray R, Antony JM, Evans M, Wood SM. Efficacy of an Anthocyanin and Prebiotic Blend
on Intestinal Environment in Obese Male and Female Subjects. J Nutr Metab. 2018;2018:7497260. Published 2018
Sep 13. doi:10.1155/2018/7497260
8. Yang L, Ling W, Du Z, et al. Effects of Anthocyanins on Cardiometabolic Health: A Systematic Review and MetaAnalysis of Randomized Controlled Trials. Adv Nutr. 2017;8(5):684–693.
ageLOC® Youth Anti-aging Supplement
1. Bouwens, M., O. van de Rest, N. Dellschaft, et al. (2009) Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. The American journal of clinical nutrition 90, 415–424.
2. Chopra, M., P.E. Fitzsimons, J.J. Strain, et al. (2000) Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations. Clinical chemistry 46, 1162–1170.
3. Earnest, C.P., J.S. Kupper, A.M. Thompson, et al. (2012) Complementary effects of multivitamin and omega-3 fatty acid supplementation on indices of cardiovascular health in individuals with elevated homocysteine. International journal for vitamin and nutrition research Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Journal international de vitaminologie et de nutrition 82, 41–52.
4. Wood, S.M.; Mastaloudis, A.F.; Hester, S.N.; Gray, R.; Kern, D.; Namkoong, J. and Draelos, Z.D. Protective effects of a novel nutritional and phytonutrient blend on ultraviolet radiation-induced skin damage and inflammatory response through aging defense mechanisms.
Journal of Cosmetic Dermatology. 16(4):491-499; 2017.
5. Hubbard, G.P., S. Wolfram, R. de Vos, et al. (2006) Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study.
The British journal of nutrition 96, 482–488.
6. Kean, R.J., D.J. Lamport, G.F. Dodd, et al. (2015) Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk, randomized, doubleblind, placebo-controlled trial in healthy older adults. The American journal of clinical nutrition 101, 506–514.
7. Kiecolt-Glaser, J.K., E.S. Epel, M.A. Belury, et al. (2013) Omega-3 fatty acids, oxidative stress, and leukocyte
telomere length: A randomized controlled trial. Brain, behavior, and immunity 28, 16–24.
8. Milenkovic, D., C. Deval, C. Dubray, et al. (2011) Hesperidin displays relevant role in the nutrigenomic effect of orange juice on blood leukocytes in human
volunteers: a randomized controlled cross-over study. PloS one 6, e26669.
9. Mastaloudis A, Sheth C, Hester SN, Wood SM, Prescot A, McGlade E, Renshaw PF, Yurgelun-Todd DA.
Supplementation with a putative calorie restriction mimetic micronutrient blend increases glutathione concentrations and improves neuroenergetics in brain of
healthy middle- aged men and women. Free Radic Biol Med. 2020 Jun;153:112-121
Beauty Focus® Collagen+
1. Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and
increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3): 113–119.
2.Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47–55.
3.Hexsel D, Zague V, Schunck M, Siega C, Camozzato FO, Oesser S. Oral supplementation with specific
bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. J Cosmet Dermatol. 2017;16(4):520–526.
4.Palombo, P., G. Fabrizi, V. Ruocco, E. Ruocco, J. Fluhr, R. Roberts and P. Morganti (2007). Beneficial
long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind,
placebo-controlled study. Skin Pharmacol Physiol 20(4): 199–210.
5.Juturu, V., J. P. Bowman and J. Deshpande (2016). Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and
zeaxanthin isomers: a double-blind, placebocontrolled clinical trial. Clin Cosmet Investig Dermatol 9: 325–332.
6.Guillou, S., S. Ghabri, C. Jannot, E. Gaillard, I. Lamour and S. Boisnic (2011). The moisturizing effect of a wheat extract food supplement on
women’s skin: a randomized, double-blind placebo controlled trial. Int J Cosmet Sci 33(2): 138–143.
Beauty Focus MultiBeauty
1. Lauer, A. C., N. Groth, S. F. Haag, M. E. Darvin, J. Lademann and M. C. Meinke (2013). Dose-dependent vitamin C uptake and radical scavenging activity in human skin measured with in vivo electron paramagnetic resonance
spectroscopy. Skin Pharmacol Physiol 26(3): 147–154.
2. Colombo, V. E., F. Gerber, M. Bronhofer and G. L. Floersheim (1990). Treatment of brittle fingernails and
onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol 23(6 Pt 1): 1127–1132.
3. Park, K. (2015). Role of micronutrients in skin health and function. Biomol Ther (Seoul) 23(3): 207–217.
4. Nobile V, Michelotti A, Cestone E, et al. Skin and antiageing effects of a combination of rosemary (Rosmarinus officinalis) and grapefruit (Citrus paradisi) polyphenols. Food Nutr Res. 2016;60:31871. Published
2016 Jul 1.
5. Pérez-Sánchez A, Barrajón-Catalán E, Caturla N, et al. Protective effects of citrus and rosemary extracts on
UV-induced damage in skin cell model and human volunteers. J Photochem Photobiol B. 2014;136:12–18.
LifePak® Anti-Aging Formula Supplements
1. Smidt, C.R.; Seidehamel, R.J.; Devaraj, S.; Jialal, I. The e"ects of a nutritionally complete dietary supplement (LifePak) on antioxidant status and LDL-oxidation in healthy non-smokers. FASEB. 1999;13(4):A546.
2. Kaats, G.R.; Wise, J.A.; Morin, R.; Pullin, D.; Squires, W.; Murrieta, T.G.; Hesslink, R. Reductions in DEXA measurements of body fat with di"erent levels of involvement in a weight loss
program using dietary supplements [LifePak]. Journal of the American Nutraceutical Association. 1998; 1(2):19–26.
3. Fletcher, R.H.; Fair!eld, K.M. Vitamins for chronic disease prevention in adults: clinical applications. J Am Med Assoc. 2002 Jun 19; 287(23):3127–9.
4. McKay, D.L., et al. The e"ects of a multivitamin/mineral supplement on micronutrient status, antioxidant capacity and cytokine production in healthy older adults consuming a forti!ed
diet. J Am Coll Nutr. 2000 Oct; 19(5):613–21.
Lifepak® Nano Anti-aging Multivitamin Supplements
1. Smidt CR, Seidehamel RJ, Devaraj S, Jialal I. The effects of a nutritionally complete dietary supplement (LifePak®) on antioxidant status and LDL-oxidation in healthy nonsmokers. FASEB 1999;13(4):A546.
2. Craft NE, Tucker RT, Chitchumroonchokchai C, Failla ML, Bhagavan HN. Assessment of coenzyme Q10 bioavailability using a coupled in-vitro digestion/caco-2 human intestinal cell model. FASEB Journal. 2005; 19(4):
Abstract #281.6, A449.
3. Kaats GR, Wise JA, Morin R, Pullin D, Squires W, Murrieta TG,Hesslink R. Reductions in DEXA measurements of body fat with different levels of
involvement in a weight loss program using dietary supplements [LifePak®]. Journal of the American Nutraceutical Association 1 (2): 19–26, 1998.
4. Fletcher RH, Fairfield KM. Vitamins for chronic disease prevention in adults: clinical applications. J Am Med Assoc.
2002 Jun 19; 287(23):3127–9.
5. McKay DL, et al. The effects of a multivitamin/mineral supplement on micronutrient status, antioxidant capacity, and cytokine production in healthy older adults consuming a
fortified diet. J Am Coll Nutr. 2000 Oct; 19(5):613–21.
6. Anderson RA, Kozlovsky AS. Chromium intake, absorption and excretion of subjects consuming self-selected diets. American Journal of Clinical Nutrition, 1985; 41: 1177–
1183.
7. Anderson RA, Bryden NA, Polansky MM. Dietary chromium intake. Freely chosen diets, institutional diet, and
individual foods. Biological and Trace Element Research, 1992; 32: 117–121.
Nu Biome®
1. Pedret A, Valls RM, Calderón-Pérez L, et al. Effects of daily consumption of the probiotic Bifidobacterium animalis
subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial. Int J Obes (Lond). 2019;43(9):1863–1868.
2. Balaguer F, Enrique M, Llopis S, et al. Lipoteichoic acid from Bifidobacterium animalis subsp. lactis BPL1: a novel
postbiotic that reduces fat deposition via IGF-1 pathway [published online ahead of print, 2021 Feb 23]. Microb Biotechnol. 2021;10.1111/1751–7915.13769.
3. Yang J, Summanen PH, Henning SM, et al. Xylooligosaccharide supplementation alters gut bacteria in
both healthy and prediabetic adults: a pilot study. Front Physiol. 2015;6:216. Published 2015 Aug 7.
4. Lin, S. H., L. M. Chou, Y. W. Chien, J. S. Chang and C. I. Lin (2016). “Prebiotic Effects of Xylooligosaccharides on the
Improvement of Microbiota Balance in Human Subjects.” Gastroenterol Res Pract 2016: 5789232.
5. Finegold, S. M., Li, Z., Summanen, P. H., Downes, J., Thames, G., Corbett, K., et al. (2014). Xylooligosaccharide increases bifidobacteria but not lactobacilli in human gut microbiota. Food Funct. 5, 436–445.
6. Gil MI, Tomás-Barberán FA, Hess-Pierce B, Holcroft DM, Kader AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem. 2000;48(10):4581–4589.
7. Harpaz E, Tamir S, Weinstein A, Weinstein Y. The effect of caffeine on energy balance. J Basic Clin Physiol
Pharmacol. 2017;28(1):1–10.
Tēgreen 97®
1. Pillai SP, Mitscher LA, Menon SR. Antimutagenic/ Antioxidant activity of green tea components and
related compounds. Journal of Environmental Pathology,
1999; 18:147–58.
2. Mitscher LA, Jung M, Wahlqvist ML, O'Brien RC. Chemoprotection: A review of the potential therapeutic antioxidant properties of green tea and its constituents. Med Res Rev, 1997; 17:327–65.
3. Sartippour M., Heber D., Lu Q., Ma M., Go V.L., and Nguyen M. Green tea inhibits breast cancer growth
and angiogenesis. Nut Cancer, 2001; 40:149–56.
4. Henning S, Niu Y, Lee N, Thames G, Minutti R, Wang H, Go V, Heber D. Bioavailability and antioxidant activity
of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. American Journal of Clinical Nutrition, 2004; 80:1558–64.